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However, a study conducted on German children found that serum ALT activities were significantly different among carriers of different patatin-like phospholipase domain containing 3 (PNPLA3) genotypes (ANOVA, P = 0.022)

Additionally, P53 can inhibit cystine uptake through downregulation of SLC7A11 expression within the Xc system, affecting GPX4 activity which leads to reduced cellular antioxidant capacity, accumulation of lipid ROS, and ferroptosis [32, 33]

W.SugiuraY.MatsumotoM.et al

in Handbook of Oxidative Stress in Cancer: Mechanistic Aspects (eds Chakraborti, S., Ray, B

S., Lee, H., Ahn, S

All raw sequencing reads were mapped to CBS using bowtie2 [53] to generate alignment files for both the forward and reverse reads