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The TYR gene, involved in melanin biosynthesis in melanocytes, has been significantly associated with vitiligo in the European population.63 The roles of many susceptibility loci remain unknown, highlighting the lack of understanding in the etiopathogenesis of vitiligo, which continues to be a challenge today

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A face-to-face comparison of tumor chicken chorioallantoic membrane (TCAM) in ovo with murine models for early evaluation of cancer therapy and early drug toxicity