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The recognition sequence is cleaved C-terminally after Asn allowing a traceless release of the attached payload if the cargo is conjugated to the C-terminus, while the N-terminus of the linker is coupled to the carrier (Stern et al., 2009

Those modifications are why semaglutide works as a once-weekly injection rather than requiring multiple daily doses

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J.: Global soil organic carbon assessment, Global Food Security, 6, 916, 2015

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