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In extrinsic apoptosis, excess iron prevents the generation of a short form of Fas by inhibiting the alternative splicing of Fas, and thus activates caspase-8-dependent apoptosis [88]

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Skin Whitening Injections Vs Laser Toning Using low-dose of Q-Switched Nd:YAG to fragment melanosomes into the cytoplasm, and hence reducing pigmentation is the process of Laser Toning