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In addition to the activation of NF-B, ROS can activate hypoxia-inducible factor 1 (HIF-1), facilitating the transcription of Snail and resulting in the downregulation of E-cadherin

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Intestinal FXR activation induces expression and secretion of fibroblast growth factor 19 (FGF19

Compared to wild-type plants, both gstf11 and gstu20 mutants exhibited substantial reduction in almost all categories of aliphatic GSLs with different side chain lengths in both 3-week-old leaves (Figures 4, 5)

Auranofin also enhances FTH1 and FTL expression, increases HMOX1 and reduces GPX4 in NSCLC models 89 , in line with what we observed in NB