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These differences may influence gene regulation or reflect inherent parasite diversity

[22 ] Severe deficiency symptoms of NAC Severe deficiency can result in neurological symptoms , such as Seizures Psychomotor retardation (slowing down of movement and speech) Intellectual disability and/or mental health condition Loss of coordination (ataxia) Bacterial infections (due to compromised immune system)

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The crystal structures of inhibitor-complexed forms also indicate that Gly-473 to Thr-475 forms an oxyanion hole, which interacts with the oxyanion of the tetrahedral intermediate in the transition state

Pharmacokinetics and pharmacodynamics of Am Bisome in a nondiabetic and diabetic murine model of systemic Candida albicans infection