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Their work further identified the switch defective/sucrose nonfermentable (Swi/Snf) chromatin remodeling complex as a key regulator of RORt-mediated histone modifications, revealing that Swi/Snf and RORt cooperate to orchestrate the epigenetic activation of Th17 differentiation genes

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doi: 10.1007/s12291-018-0808-0 99 MurriMInsenserMFernndez-DurnESan-MillnJLEscobar-MorrealeHF

To confirm this, a small clinical series by Sigalos et al

Kisspeptin increases GnRH, which increases FSH and LH, promoting follicle development and sperm production