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The significant correlation between Kla-specific genes and lactate accumulation-related genes (e.g., P300, LDHA) reveals that Kla promotes BC progression and immune escape by affecting NK cell function and multiple signaling pathways (NOTCH, WNT, among others) (117)

Weeks 5 to 8

The expression of the aforementioned pro-inflammatory genes, which were highly upregulated by HFD, was substantially reduced in the HFD + Ret group

However, trials in humans have not shown significant changes in testosterone levels

455 Their role in targeting GBM angiogenesis has also been explored, with miRNA-29a-3p-enriched MSC-derived EVs suppressing vasculogenic mimicry and angiogenesis independently of VEGF, suggesting a promising antiangiogenic strategy

Follicular fluid oxidative stress biomarkers and ART outcomes in PCOS women undergoing in vitro fertilization: A cross-sectional study