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Fact: Its primarily an antioxidant

The cause of death was reported as arteriosclerosis of the carotid artery with cerebral infarct

Biochem J 2009;417(1): 1-13

PubMed Europe PMC Scholia Crystal structures of gamma-glutamyltranspeptidase from Escherichia coli, a key enzyme in glutathione metabolism, and its reaction intermediate

Irisin is a myokine associated with both endurance and resistance exercise (Zunner et al., 2022), strongly corresponding to the AMPK activity and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1) pathways, which are typically activated by endurance training (Zunner et al., 2022

However, the specific mechanisms by which mitochondria act among the three need to be further explored