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Understanding tesofensine's unique mechanism and risk profile helps determine if this powerful but controversial weight loss compound merits consideration despite its FDA rejection and safety concerns

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Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

As an alternative methyl donor, betaine plays a central role in maintaining methylation capacity, and its depletion may contribute to elevations in S-adenosylhomocysteine and impaired methyltransferase activity

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