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MBTs are also being explored for the treatment of neurodegenerative diseases, such as AD and PD

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Notably, BHB increased the SOD activity, GSH concentration, and GSH/GSSG ratio (Fig

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Interestingly, changes in the intestinal flora may alter nerve development and even cause neurodegenerative disorders (145)

360 Disulfide formation in proteins is reversible, as two cysteine thiols are oxidized into a linked disulfide via thiol-disulfide exchange or oxygen-dependent reactions, often requiring catalysts such as transition metals or flavin adenine dinucleotide (FAD) due to kinetic barriers