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Mast cell-deficiency protects mice from streptozotocin-induced diabetic cardiomyopathy

Kumar A, Dubey AK, Kumar V et al (2020a) Over-expression of chickpea glutaredoxin (CaGrx) provides tolerance to heavy metals by reducing metal accumulation and improved physiological and antioxidant defence system

Shen JS, Meng XL, Schiffmann R, Brady RO, Kaneski CR

Conclusions and future perspective Despite a large part of literature exploring on the accumulation and the origin of ROS, current antioxidant-based therapies lack of specificity for dysfunctional tissues, cells, and organelles, and thus may not reach an effective concentration at the target site of pathologic oxidative stress

In addition to the tertiary structures that will be displayed, attention must also be given to the way in which peptide structures may aggregate to form dimeric, trimeric and tetrameric clusters

doi: 10.3945/ajcn.112.049163