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Improving mitochondrial function: As already discussed, mitochondria play a key role in the regulation of T cell metabolism, biosynthesis, migration, cell fate and programmed cell death

Beads were washed three times in cold KPBS, then 10% of bead volume was lysed with 1% Triton buffer for protein extracts and the remaining 90% was extracted in 80% methanol containing heavy labeled amino acid standards (Cambridge Isotope Labs) on a rotator shaker for 10min at 4C

S2c, S2f, S2h and S2i), suggesting the involvement of compensatory pathways for cholesterol export

99 Similarly, a cholesterol oxidase-loaded CoPN3 single-atom nanozyme effectively suppresses tumor metastasis by enhancing ROS generation 100 (Fig

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