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[1] Picomolar activity is unusual for a small peptide and suggests high-affinity receptor-mediated signaling, though the specific receptor for GHK-Cu has never been identified

This was demonstrated by the fact that administration of the peptide counteracted 5-HT receptor-dependent symptoms induced by pargyline + L-tryptophan, i.e., hyperthermia and wet dog shake related to 5-HT2A agonism, but not 5-HT1A-related forepaw treading, hind limb abduction, or hypothermia

The interaction between the two is calibrated at intake to ensure they are working on complementary rather than overlapping pathways

Despite being used locally (e.g.,injected near the injury site), BPC-157 seems to exert full-body effects

Key Ingredients: Vitamin C (tetrahexyldecyl ascorbate, 3-O-ethyl ascorbic acid, ascorbyl glucoside, magnesium ascorbyl phosphate, sodium ascorbyl phosphate), tranexamic acid (, guava extract, guava seed oil, ferulic acid | Who It's For: All skin types | Fragrance-Free: Yes Best Retinol Alternative: Paula's Choice Clinical Discoloration Repair Serum Why It's Worth It: Retinol is one of the crown jewels of skin care, but if you have sensitive skin, you might find that this active ingredient is too harsh