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This is evidenced by a recently published bibliometric analysis that counted articles regarding endothelial dysfunction in sepsis that were published between 2003 and 2023, which showed a rapidly increasing number

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"Free radicals" are roaming individual atoms of oxygen that are desperately looking to pair up with other atoms, because atoms like to exist in pairs

Samassa, F., Holtzmann, C

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As a result, the intrinsic membrane mechanical properties are altered, resulting in reduced deformability and reduced fluidity or altered permeability of the phospholipid bilayer, which, in turn, reduces the ability of the membrane to withstand osmotic changes (32)