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Description

Normal levels of tyrosinase are produced but only part of it is delivered and active in the right place for melanin biosynthesis, resulting in reduced pigment production

10.1016/j.jcyt.2014.02.003 111

Okhokhonin, A

These mice were randomly divided into two subgroups that received SW1990 cells in which GPx1 was stably silenced or that contained empty vector ( n = 5/each group)

Cells were then transfected with 100 L of 25 and 50 nM fluorescent siRNA complexed with AuNPs-d-PLL-PEG MR 25 (500 g/mL) and AuNPs-d-PLL-PEG-FA MR 25 (500 g/mL) and incubated for four hours in 500 L serum-free RPMI