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Li et al

Protein Sci

That decline is one reason GHK-Cu supplementation tends to produce more visible results in patients over 3540

The copper(II) ion is coordinated by the glycine amino terminus, the deprotonated glycine to histidine peptide-bond nitrogen, and the histidine imidazole nitrogen, giving the complex its characteristic colour and stability

The capsules utilize a gastric-resistant (enteric-coated) shell designed to survive the acidic stomach environment and dissolve in the higher pH conditions of the small intestine