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Dedicating "Empowering Intensity Modulated Proton Therapy Through Physics and Technology: An Overview" to the Memory of Dr Michael Goitein

However, oligodendrocyte death was not prevented in mice lacking FAS in oligodendrocytes revealing that FAS is also not essential for the induction of apoptosis in the cuprizone model (Hesse et al., 2010)

A peptide is a short chain of amino acids, the same building blocks that make up proteins, joined by peptide bonds

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Nevertheless, it has become apparent during their usage that these open-chain electrophilic ligands could inhibit not only kinases, but also other proteins and elicit time-dependent off-target reactivity 11,12

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