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34 2-nitrofluorene (NF) is one of the dominant nitro-PAHs in the environment and will be discussed further as a model compound for nitro-PAHs

A., Sweileh, W

Moreover, mitochondrial DAMPs released from stressed cells-such as mtDNA and cardiolipin-serve as potent activators of pattern recognition receptors (e.g., TLR9, cGAS-STING, and NLRP3), perpetuating inflammation ( 6.3 Tissue- and metabolic context-dependent mitochondrial responses to infection Mitochondrial responses to infection are not uniform but vary according to tissue type, cell lineage, and the hosts metabolic state

Although a large number of preclinical studies have achieved ideal results in material design, mechanism selection, delivery, and therapeutic effects, the inability to translate these results into clinical applications is one of the reasons why nanomaterials are rarely used in the treatment of bacterial pneumonia

Secondly, GA inhibited arterial stiffness by preventing the degradation of elastic fibers and suppressing collagen deposition