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The results directly indicated that the targeting motif RGD-binding peptide RGD-GHK almost totally suppressed the collagenase (MMP-1) expression, resisted H 2 O 2 -induced COL-1 degradation, and simultaneously promoted collagen synthesis compared with GHK alone for cell anti-aging performance

Poria cocos polysaccharides mainly show immunomodulatory, anti-inflammatory, hepatoprotective activities, and other pharmacological effects such as anti-cancer, antioxidant stress [67, 69]

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Both lowered SpO2 [26] and increased PBT [27] are indicants of the severity of the immune-inflammatory response of acute COVID-19, and both predict critical disease and mortality [27, 28]

p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice

In another aspect, the gel capsule may be formed from hydroxypropyl methylcellulose (HPMC) or hypromellose