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It comprises a heavy chain component, SLC3A2 (solute carrier family 3 member 2), and a transport module, SLC7A11 (solute carrier family 7 member 11) [53]

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Once the tumour became arrested in the palbociclib-treated group, mice were further randomized to receive either RSL3 (50 mg kg 1 , five times per week for 2 weeks) or the vehicle, resulting in four experimental groups: vehicle, RSL3, palbociclib and palbociclib + RSL3