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J Exp Med 203:10071019 Alvarez JI, Dodelet-Devillers A, Kebir H, Ifergan I, Fabre PJ, Terouz S, Sabbagh M, Wosik K, Bourbonniere L, Bernard M, Van HJ, De Vries HE, Charron F, Prat A (2011) The hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence