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Kovalsky, Biological Significance of Selenium (Nauka, Moscow, 1974) [in Russian]

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In susceptible individuals, progesteronewhether produced by the body or introduced syntheticallycan trigger mast cell degranulation , a process in which immune cells release inflammatory mediators, most notably histamine

Nitrogen balance is the difference between the amount of nitrogen taken into the body (mainly as dietary protein) and the amount lost mainly in urine and to a lesser extent in feces and sweat

51 Thus, improvements noted as a result of leucovorin calcium in some children could be the result of an effect of leucovorin calcium on non-CNS organs