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Importantly, treating children with antifungal agents is potentially harmful

This is primarily caused by the homocysteine being drawn excessively into transsulfuration via the CBS gene

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Some other critical roles assigned to glutathione in the body include: Neutralization of superoxide radicals Cofactor for several antioxidant enzymes Regeneration of vitamins C and E Neutralization of free radicals produced by liver metabolism of chemical toxins Transportation of mercury out of cells and the brain Regulation of cellular proliferation Vital to mitochondrial function and maintenance of mitochondrial DNA (mtDNA) Glutathione has been shown to be very important in helping prevent hyperpigmentation, helping to prevent melanogenesis, the generation of melanin in the skin

doi: 10.1016/S1474-4422(18)30403-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.Dorsey ER, Elbaz A, Nichols E, et al

Ten thousand cells/well were plated in white 96-well plates (Table 1)