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Finally, other activation mechanisms contribute to the activation of the NLRP3 inflammasome, further aiding in the development of PD models in animals (Huang et al., 2024

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Phospho-RIPK1 was detected only in cells expressing WT RIPK1, thus validating the specificity of the pS309 antibody (Fig

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479,480 The myeloid-specific HRD1 complex has been implicated in the ubiquitination of STING, resulting in its degradation in the basal state and limiting its role in antitumor immunity

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