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RNA interference and drug treatments Small interfering RNAs (siRNAs) were custom-designed and purchased from SigmaAldrich (Supplementary Dataset 4)

doi: 10.3390/genes14122217

Patients with liver or kidney disease should use glutathione with caution and under strict medical supervision

demonstrated that UB not only prevents the development of CRC but also modifies the gut microbiota and enhances the immunological environment of tumors, leading to reduced PD-L1 expression and improved outcomes when combined with traditional therapies

IC 50 values ranging between 100 M and more than 600 M suggest wide variability in cell line sensitivity and/or in vitro experimental conditions among different studies (Table 1)

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