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Conjunctival hyperemia, corneal infiltrates, headache, ocular edema, and ocular pain have occurred in approximately 1% to 5% of patients

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It also has a profound effect on wound healing and tissue damage, commonly caused by corticosteroid use

Once in the blood, free B12 binds to two proteins: transcobalmin, forming holo-transcobalamin (holoTC), and haptocorrin to form holo-haptocorrin (holoHC)

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Once hydroxocobalaminthe form most commonly used in the UKis injected intramuscularly, it rapidly enters the bloodstream, bypassing the gastrointestinal tract entirely