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Ji L, Mathioni S, Johnson S, Tucker D, Bewick A, Kim K, Daron J, Slotkin R, Jackson S, Parrott W, Meyers B, Schmitz R

4) Underexplored therapeutic strategies and safety concerns: Preclinical studies have relied on short-term administration of ferroptosis modulators, but the long-term safety and efficacy of these agents in ADPKD are unknown

The membranes were incubated with secondary antibodies at room temperature for 1 h

Diebold and Chandel, 2016

Its effects are largely mediated by selenium-containing proteins (selenoproteins), which contain at least one selenocysteine (SeCys/Sec), a selenium-containing amino acid instead of sulfur (S) (39, 40)

Conversely, pH2AX staining especially in kidney cells was distinctly increased by oxaliplatin but not by BSO-OxMal