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[DOI] [PubMed] [Google Scholar] 324.Zhu Q and Zhou X, J

Air travel is notoriously dehydrating, and the cabin pressure can lead to joint stiffness

This makes the molecule lipophilic, which means it can easily go through fat-based cell walls

This increase in ROS triggers mitochondrial dysfunction, further exacerbating oxidative stress and promoting cell death through both necroptosis and ferroptosis pathways (Figure 5) (Chen M.-S