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According to ClinicalTrials.gov, as of 5 th December 2022, no phase III clinical trial on the use of GSH in NAFLD is currently ongoing or recruiting

Gebka A, Serkies-Minuth E, Raczynska D

Notably, the hnRNP-E1 level was higher in iPSCs, likely reflecting their characteristically larger nuclear-to-cytoplasmic ratio associated with pluripotency, where nuclear proteome represents larger fraction of the total cellular proteome

Neurotoxicology 14(23):4560 Gogna S, Kaur J, Sharma K, Prasad R, Singh J, Bhadariya V, Kumar P, Jarial S (2023) Spirulina : an edible cyanobacterium with potential therapeutic health benefits and toxicological consequences

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While some mutations may result in alleles that confer greater accumulation or tolerance to toxic heavy metals that could be beneficial, we expect that most mutations that result in excess uptake of heavy metals to be deleterious