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Overarching Principle The fundamental principle of regulation of medicines is to optimise timely access to effective treatments while reducing the risk of harm from improper use

Once quality actions have become a standard of care, the focus of quality assessment shifts to areas where a gap exists

Pulmonary Embolism (PE) A pulmonary embolism (PE) occurs when a blood clot from a deep vein travels to the lungs, stopping blood flow to an artery

[2] For most individuals taking standard B12 supplements as recommended by healthcare professionals, the risk of harmful effects remains extremely low

Vlachojannis, C., Zimmermann, B

Reese, J