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BBB dysfunction depends on local pathology To test this, we treated mice for 5 weeks with cuprizone as before and then analyzed the integrity of endothelial tight junctions on cortical sections

doi: 10.2147/vhrm.2006.2.3.213

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Studies show that BPC 157 can: Support ulcer recovery by promoting regeneration of the gastric mucosa Influence intestinal lining integrity by supporting tight junction proteins that seal the spaces between intestinal cells Protect against NSAID-induced gut damage, a common problem for people who regularly use pain medications like ibuprofen Reduce gut inflammation markers (relevant for IBS, Crohns-like symptoms, and inflammatory bowel conditions) Support the mucosal barrier that protects the intestinal lining Assist in balancing gut motility, potentially helping with both constipation and loose bowels The gut-brain connection makes these effects even more significant