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Animal Toxicology Studies Animal toxicology studies tested doses from 0.0027 mg/lb to 9.1 mg/lb via intraperitoneal, intramuscular, intravenous, and oral routes for up to 6 weeks, finding: No acute toxic or lethal dose No gross or histologic toxicity in major organs No hepatotoxicity or nephrotoxicity Negative Ames test (no mutagenicity) Negative chromosomal aberration tests (no genotoxicity) No teratogenicity in rat pregnancy studies No local injection site irritation The LD1 (minimum lethal dose) could not be achieved despite aggressive testing

Usage Instructions: Take 2 capsules daily with or after meals

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Crosstalk between autophagy and inflammatory signalling pathways: balancing defence and homeostasis

2,4, 6-trisphenol (dimethylaminomethyl)

1 Introduction Atherosclerosis describes the accumulation of immune cell-rich, lipid-rich plaques known as atheroma in large and medium-sized arteries (Roy et al., 2022)