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In the released and non-arrested states, we gated on proliferating cells, using CFSE

Singla V, Pratap Mouli V, Garg SK, Rai T, Choudhury BN, Verma P, et al

Immunization schedule BALB/c mice were selected for Pf CSP immunization based on an extensive precedent in CSP vaccine literature, where the H-2K d -restricted CD8 + T-cell epitope NYDNAGTNL is recognized, facilitating hypothesis testing aligned with established immunological methods

70% EtOH, 1 min

The KEAP1 protein detects oxidative stress by going through a conformational change that prevents association with NRF2, leading to NRF2 accumulation and translocation to the nucleus, which then induces transcription through antioxidant response elements found in a broad set of genes involved in redox homeostasis and correcting oxidative damage