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This research has been reviewed by the Mayo Clinic Conflict of Interest Review Board and was conducted in compliance with the Mayo Clinics conflict of interest policies

Am J Physiol Gastrointest Liver Physiol 293:G178187

Because HOPDs will no longer be required to report this measure under the modification to extend voluntary reporting beginning with the CY 2027 reporting period, we estimate the revised data submission burden, reflecting 20 percent of hospitals voluntarily reporting, will be 107 hours (3,200 HOPDs 20 percent 0.167 hours 1 quarter) at a cost of $5,891 (107 hours $55.06/hour) annually

Therefore, participants were included in this study if they were aged 50 years and underwent assessment at wave 1 including measurement of plasma folate and plasma total B 12 and screening for depression

Docket: For access to the docket to read background documents or the electronic and written/paper comments received, go to Regulations.gov and insert the docket number, found in brackets in the heading of this document, into the Search box and follow the prompts and/or go to the Dockets Management Staff, 5630 Fishers Lane, Rm

An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity