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in patients with acute myeloid and lymphoblastic leukaemia

72 LiT.YangD.ZhongS.ThomasJ

Under prolonged injury, inflammation, or mechanical stress, fibroblasts can phenotypically transform into myofibroblasts characterized by -SMA expression, synthesis of collagen-rich ECM, and fibroblast proliferation (88)

Given continuous exposure to luminal antigens, the intestinal barrier plays a critical regulatory role by selectively permitting the passage of essential molecules while restricting the translocation of potentially harmful compounds [7]

This effect is probably caused by the presence of sapogenins in fenugreek seeds, which stimulate bile secretion, enhance the metabolism of cholesterol to bile acids and cholesterol excretion

However, clinical trials evaluating these effects in humans treated with NAD+ injection have not yet been published