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10.1016/j.freeradbiomed.2012.02.043 139 YuanY.MenW.ShanX.ZhaiH.QiaoX.GengL.et al (2020)

They work by stimulating the expression of enzymes involved in glutathione synthesis, promoting its production

However, their drug loading capacity, morphological features, surface potential, and connected modifiers affect the efficiency of brain-targeted delivery

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Ganoderic acid a alleviates A25-35-induced HT22 cell apoptosis through the ERK/MAPK pathway: a system pharmacology and in vitro experimental validation