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argued that ACSL4 guided ferroptotic cell death by remodeling the cellular lipid composition[26]

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[DOI] [PubMed] [Google Scholar] 127.Le Gal K., Ibrahim M.X., Wiel C., Sayin V.I., Akula M.K., Karlsson C., Dalin M.G., Akyrek L.M., Lindahl P., Nilsson J., et al

The thiomethyl shunt involves the activity of CCBL to cleave cysteine S-conjugates, and subsequent methylation with an active form of methionine to produce thiomethyl metabolites ( 9, 21 ), meaning that APAP-SG and NAC-APAP were probably biotransformed to APAP-cysteine beforehand

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