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It has been shown that ALA inhibits the progression of lung cancer by suppressing autophagy in A549 cells, a process mediated by activation of the mTOR/p70S6K pathway (Figure 4CE) [46]

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2006;47(1):17483 Rossi M, Johnson DW, Morrison M, Pascoe E, Coombes JS, Forbes JM,

In hypertrophic and failing myocardium, the level of SERCA2 protein and its ability to absorb Ca 2+ are inhibited