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Papadopoli D, Boulay K, Kazak L, Pollak M, Mallette F, Topisirovic I et al

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Pioglitazone and rosiglitazone, which were originally designed as PPAR agonists, have been shown to block dopaminergic neurodegeneration and reduce astrocytic and microglial activation 122

185 These toxic oestrogen metabolites are also detoxified by glutathione, which is therefore dependent on cysteine availability