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Additionally, rats given TNBS experienced severe bloody diarrhea, an increased colon weight-to-length ratio, a macroscopic damage score, goblet cell loss, submucosal edema, increased inflammatory cell infiltration, and a marked weight loss (259)

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Ren J, Li S, Wang C et al (2021) Glutathione protects against the meiotic defects of ovine oocytes induced by arsenic exposure via the inhibition of mitochondrial dysfunctions

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Orally delivered NAC undergoes extensive first-pass metabolism resulting in about 90% loss by enzymic deacylation to form cysteine in the small intestine [9]

doi: 10.1002/JLB.3MA1020-647R 47 YoshimuraTMatsushimaKTanakaSRobinsonEAAppellaEOppenheimJJet al