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Determination of mitochondrial reactive oxygen species production The production of reactive oxygen species (ROS) in the mitochondrial matrix was determined as a time-dependent increase in the fluorescence intensity of selective MitoSOX (Life Technologies, Pleasanton, CA, USA) dye in the cells exposed to tested therapeutics using flow cytometry (BD LSRII, BD Biosciences, San Jose, CA, USA)

Nutrition Info: Nutrition information are estimates only and may vary based on the specific brands, ingredients, and portion sizes you use

Cystinosin is a cystine-proton cotransporter, the absence of which results in the accumulation of cystine in the lysosomes [1,2]

The percentage of aberrations was calculated as follows: An Olympus CX- 41 research microscope (100X objective) was used to observe the chromosome structure

The combination of all these synthesis effects, occurring simultaneously through overlapping pathways, produces the skin quality improvements that clinical trials document