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Globally, both share the challenge of severe antibiotic resistance in their individual treatments (Ibrahim et al., 2020

10.1073/pnas.1603244113 191 YangY.HuangH.CuiZ.ChuJ.DuG

Used needles and syringes should be placed in an FDA-cleared puncture-proof sharps container rather than household trash to prevent needle-stick injuries

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& Sundberg, K

Taken together, hypertonicity-responsive E3 ligase RNF183 functions for hypotonic environment adaptation through modulating Na, K-ATPase activity, and maintaining ionic homeostasis