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Here we develop a self-cascade nanomotor with high efficiency toward simultaneous uric acid (UA) degradation and H 2 O 2 elimination on the basis of UOx and sodium citrate loading in amine functionalized hollow mesoporous silica nanoparticles (AHMSNs)

The effects of catechol-O-methyltransferase Inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells

Currently, several pharmaceutical companies are investigating specific SIRT1 activators in Phase I and Phase II trials for the treatment of type II diabetes and obesity (228) to define their utility in the treatment of obesity and metabolic diseases

Zn deprivation significantly inhibits the development of the cerebellar cortex and delays the withdrawal of the external cell layer, the acquisition of granule cells, and the differentiation of Purkinje cells (200)

Effect on Bone Mineral Density An annual infusion of Reclast was non-inferior to the oral weekly bisphosphonate active control based on the percentage change in lumbar spine BMD at Month 24 relative to baseline (Reclast: 6.1% increase