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These HER2.28/PD-L1.BB CAR-T cells demonstrated rapid and durable eradication of pleural and peritoneal metastatic tumors in xenograft models, leading to the initiation of a phase I clinical trial for patients with pleural or peritoneal metastasis (NCT04684459) ( Figure 2D )

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Release form: Vials made of dark glass, closed with rubber stoppers and rolled in aluminum caps with a content of 100 ml

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All procedures were approved by the Research and Development Committee of the Institutional Animal Care and Use Committee at KIIT University and carried out under a license from the local government in compliance with the institutional guidelines