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Description

Pandey B, Baral R, Kaundinnyayana A, Panta S

10.1016/j.phrs.2012.10.015 Pharmacol

Widiyanti, and H

In this disease, characterized by obesity and hepatic steatosis, HMGB1 may trigger oxidative stress and inflammatory processes in hepatocytes

Fe 3+ can act as a catalase-like nanozyme to transform H 2 O 2 into O 2 , relieving the hypoxic condition in TME and boosting oxygen-based PDT and SDT

It also enhanced the hepatic total antioxidant capacity in APAP-treated mice, exhibiting direct radical scavenging activity against APAP-induced oxidative stress