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Beta-catenin ( Ctnnb1 ) plays a role in macrophage lineage differentiation [123] and myeloid -catenin expression modulates macrophage inflammatory responses[124]

(2016b) reported that curcumin enhances functional recovery after SCI by inhibiting the AKT/mTOR pathway to promote LC3-I to LC3-II conversion and decreasing p62 expression to promote autophagic flux

While cGAS signals via stimulator of interferon genes (STING) to induce predominantly IFN I, TLRs signal via the adaptor protein myeloid differentiation primary response (MyD)88 and the transcription factor NF-B to activate the expression of IL-1, IL-6 and IL-18 and of AIM2, NLRP3 and other elements of the inflammasome

Quantification of 4-HNE was performed by measuring the average staining intensity per pixel in three sections from each sample at a similar distance from the optic nerve and this result was also divided by the retinal area

By enhancing insulin signaling, hesperidin improves glucose uptake, glycogen synthesis and cellular responses to insulin

[DOI] [PMC free article] [PubMed] [Google Scholar] Aguilo A, Tauler P, Sureda A, Cases N, Tur J & Pons A (2007)