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Therefore, one of the therapeutic strategies in cancer should be considered the depletion of the cellular antioxidative systems, among which GSH is one of the main actors [19]

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Due to its strong antioxidant properties (221) and its role as a mitophagy inducer (222), UA exhibits anti-aging effects, enhances mitochondrial activity, and improves muscular performance

10.1016/j.ccr.2006.08.009 Cancer Cell 127 van den DobbelsteenD

The defense system not only boosts the capacity to detoxify oxidants but also repairs oxidative damage