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If considering use beyond this period, particularly at doses providing more than 25 mg of elemental zinc daily, clinical review is advisable and monitoring for copper status may be appropriate in long-term use

Structurally similar to insulin, this IGF-1 LR3 has the potential primarily to regulate cell tissue growth and development

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D.NorrisH.et al (2015)

doi: 10.3390/molecules24081548 104

In all experiments, age-matched mice were used (unless otherwise stated), WT littermates served as controls, and treatment was randomly assigned to control for cage effect