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Under normal conditions, the gut microbiota plays a critical role in maintaining host health, including maintaining intestinal barrier function, regulating immune responses, and promoting nutrient absorption and metabolic processes ( Interestingly, Zhai et al

Lentiviral-mediated shRNA interference All shRNAs for GCLC and SIRT2 were either from the reported literature [62] or designed and purchased from Sangon Biotech

Wang Y, Beydoun MA, Caballero B, Gary TL, Lawrence R

Dermatology 198 , 261264 (1999)

It is defined by vitamin B 12 deficiency in the presence of sufficient dietary vitamin B 12 intake, negative Schilling test, and lack of anti-intrinsic factor antibodies.30 Clinically, it is diagnosed by exclusion of other disorders or factors causing vitamin B 12 deficiency

Teschke R, Schulze J, Schwarzenboeck A, Eickhoff A, Frenzel C